SEP: un livre en anglais destiné aux médecins et aux malades.

Publié le par Handi@dy

Avertie de sa parution avant le weekend, j'ai hésité à publier, mais il ne faut pas préjuger de la capacité des SEPiens français de lire un livre spécialisé en anglais lol! Puis, comme j'ai également des lecteurs/maileurs de blog canadiens...

Je vous livre le topo en anglais. Si vous avez besoin que je traduise un passage, je suis ok! Les Américains ont une autre approche de la SEP, il est intéressant de la connaître.

Copié-collé:


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McAlpine's multiple sclerosis (4th Ed.)

Auteur(s) : COMPSTON Alistair, MCDONALD Ian R.
Date de parution: 11-2005
Langue : ANGLAIS
982p. Hardback
Etat : Disponible chez l'éditeur (délai de livraison : 12 jours)

Public concerné
Neurologists, Libraries, MS patients, Pharmaceutical workers


Résumé
Covers various aspects of multiple sclerosis. In this book, five sections cover the history, genetic epidemiology, clinical neurology, pathogenesis, and the treatment and management of multiple sclerosis.


Sommaire
SECTION ONE: THE STORY OF MULTIPLE SCLEROSIS1. The story of multiple sclerosisThe evolving concept of multiple sclerosisNaming and classifying the disease: 1868-1983Clinical descriptions of multiple sclerosis: 1838-1981Personal accounts of multiple sclerosis: 1824-1991The social history of multiple sclerosis: 1945-1998The pathogenesis and clinical anatomy of multiple sclerosis: 1849-1977The laboratory science of multiple sclerosis: 1912-1981Discovery of glia and remyelination: 1858-1988The aetiology of multiple sclerosis: 1883-1976 Attitudes to the treatment of multiple sclerosis: 1841-1983 SECTION TWO: THE CAUSE AND COURSE OF MULTIPLE SCLEROSIS2. The distribution of multiple sclerosisThe rationale for epidemiological studies in multiple sclerosisDefinitions and statistics in epidemiologyStrategies for epidemiological studies in multiple sclerosisThe geography of multiple sclerosis Epidemics and clusters of multiple sclerosisThe environmental factor in multiple sclerosis3. The genetics of multiple sclerosis: Genetic analysis of multiple sclerosisMethods of genetic analysisRacial susceptibilitySex differences in susceptibilityFamilial multiple sclerosisCandidate genes in multiple sclerosisSystematic genome screeningLessons from genetic studies of experimental allergic encephalomyelitisConclusions4. The natural history of multiple sclerosisIntroductionDefinitionsOnsetCourse Inter-individual variabilityFactors affecting the prognosisGeneral considerationsEnvironmental influencesChapter 5: The aetiology of multiple sclerosis: an epitome SECTION THREE: THE CLINICAL FEATURES AND DIAGNOSIS OF MULTIPLE SCLEROSIS6. The symptoms and signs of multiple sclerosis. Multiple sclerosis as a neurological illnessInitial symptomsSymptoms and signs in the course of the diseaseIndividual symptoms and signAssociated diseasesConclusion 7. The diagnosis of multiple sclerosisDiagnostic criteria for multiple sclerosisSelection of investigationsMagnetic resonance imagingEvoked potentialsExamination of the cerebrospinal fluidA strategy for the investigation of demyelinating disease8. The differential diagnosis of multiple sclerosisThe spectrum of disorders mimicking multiple sclerosisDiseases that may cause multiple lesions of the CNS and also often follow a relapsing remitting courseSystematized central nervous system diseasesIsolated or monosymptomatic CNS syndromesNon organic symptomsHow accurate is the diagnosis of multiple sclerosis? 9. Multiple sclerosis in the individual and in groups: a conspectusThe typical case Isolated syndromes and their outcome: judicious use of investigations and critique of the new diagnostic criteriaCo-morbidity and associated diseases Situations in which alternative diagnoses should be consideredWhen to ignore inconvenient laboratory results or clinical findings: taking the best positionPathognomonic and un-heard of features of multiple sclerosis SECTION FOUR: THE PATHOGENESIS OF MULTIPLE SCLEROSIS10. The neurobiology of multiple sclerosis. Organisation in the central nervous systemDevelopment of the central nervous systemMacroglial lineages in the rodent and human nervous systemAxon-glial interactions and myelinationDemyelinationAxon degeneration and restoration of functionRemyelination11. The immunology of inflammatory demyelinating diseaseMultiple sclerosis as an autoimmune diseaseImmune responses: innate and adaptiveT lymphocytesB lymphocytesAutoimmunity and self tolerance in the central nervous systemRegulation of central nervous system autoimmune responsesImmune reactivity in the central nervous systemPathogenesis of demyelination and tissue damagePeripheral blood biomarkers for multiple sclerosis and disease activityMarkers of multiple sclerosis and disease activity in cerebrospinal fluidConclusion12. The pathology of multiple sclerosisIntroductionPathological classification of demyelinating diseasesThe demyelinated plaqueImmunopathology of inflammationDemyelination and oligodendroglial damgeRemyelination Axonal pathologyGrey matter pathology / cortical plaquesAstroglia reactionAbnormalities in the normal white matterDistribution of lesions in the nervous systemIs there evidence for an infectious agent in the lesions of multiple sclerosis? Dynamic evolution of multiple sclerosis pathologyDifferences between acute relapsing and progressive multiple sclerosis Molecular approaches to the study of the MS lesion: Global profiling of transcriptome and proteome. Association of multiple sclerosis with other diseasesConclusions13. The pathophysiology of multiple sclerosisIntroductionMethods for exploring the pathophysiology of multiple sclerosisRelapsing remitting multiple sclerosis: loss of function due to conduction block Relapsing remitting multiple sclerosis: recovery of function and remission Physiological explanations for other clinical symptoms in multiple sclerosisPermanent loss of function in the context of disease progression Summary SECTION FIVE: THE TREATMENT OF MULTIPLE SCLEROSIS15. Care of the person with multiple sclerosisGeneral approach to the care of people with multiple sclerosisThe early stages of disease: minimal disabilityThe middle stages of disease: moderate disabilityThe later stages of disease: severe disability Guidelines for the management and investigation of multiple sclerosisConclusion16. Treatment of the acute relapseThe features of active multiple sclerosisThe treatment of relapse in multiple sclerosisOther approaches to the treatment of acute relapseTreatment of acute optic neuritis Management of other central nervous system demyelinating disordersAdverse effects of corticosteroidsMode of action of corticosteroidsPractice Guidelines17. The treatment of symptoms in multiple sclerosis and the role of rehabilitationThe general principles of symptomatic treatment in multiple sclerosisDisturbances of autonomic functionMobility and gait disturbanceFatigueDisturbances of brain stem functionPerturbations of nerve conduction CognitionVisual symptomsRehabilitation in multiple sclerosisSummary18. Disease modifying treatments in multiple sclerosisThe aims of disease modifying treatmentThe principles of evidence based prescribing in multiple sclerosisThe role of magnetic resonance imaging in clinical trials Drugs that stimulate the immune responseDrugs that non-specifically suppress the immune responseThe beta interferonsMolecules that inhibit T cell-pep

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***Ce qui est intéressant, c'est le chapitre consacré à l'histoire de la SEP, les cas du passé connus.
Je pense que vous aurez remarqué que j'ai classé mes articles sur les cas de SEP connus des siècles précédents (ou supposés SEP!) dans une catégorie à part que je vais compléter sous peu: Heinrich Heine comme annoncé dans mon dernier article sur l'histoire de la SEP, mais aussi d'autres, un noble, une sainte... Passionnant! Premier cas supposé SEP: une femme viking (on dit bien que la maladie est plutôt localisée dans l'hémisphère nord et serait d'origine scandinave...) Découvrez mes articles sur le sujet et notamment mon article humour avec une BD dont j'ai rédigé les bulles (Hâgar le terrible qui s"exprime sur la SEP!). J'ai démarré cette série l'été 2007 et j'y reviens avec plaisir après mes multiples hospitalisations qui m'ont empêchée de créer ces articles! Bonne lecture.

 


Commenter cet article

Fancri :0044: 26/05/2008 20:25





CADEAU!!! bises

Handi@dy 28/05/2008 21:17


Yaouh! Vais voir ça!!! :0010: